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Cet abstract a été assigné à session BOG-SBO 1 Medische retina/ Rétine médicale
TitrePhotodynamic treatment of circumscribed choroidal hemangiomas
Abstract Nr.A1009
ButTo evaluate the safety and efficacy of photodynamic therapy (PDT) in the treatment of symptomatic circumscribed choroidal hemangiomas (CCH).
MéthodesThis prospective nonrandomized study included 8 patients referred to us for management of CCH with exudative activity. PDT was applied by diode laser (689nm) with a light dose of 50 J/cm² and using verteporfin (6 mg/m²) IV bolus injection. The treatment spot diameter was related to the tumor basal diameter (TBD).
RésultatsThe mean tumor thickness before PDT was 3.3 mm and the mean largest TBD was 6.9 mm . All patients were managed with a single PDT application. After a mean follow-up of 12 months, all CCH (100%) showed regression of the vascular tumor mass with a final tumor thickness of 2.3 mm and complete resorption of the serous retinal fluid (SRF). All CCH showed overlying PDT–related RPE atrophic changes. No cases of retinal vascular occlusion or recurrent leakage was documented. Six patients (75%) had visual improvement, one (12.5%) had stable vision and one (12.5%) had worse vision due to chronic exudation-related RPE changes.
ConclusionPDT using verteporfin offers a safe and effective option to treat CCH. Complete resorption of the subretinal fluid is associated with visual improvement.
Author 1
NomGUAGNINI
InitialesAP
InstitutOcular Oncology Unit, Cliniques Universitaires St-Luc
VilleBrussels
Author 2
NomDE POTTER
InitialesP
InstitutOcular Oncology Unit, Cliniques Universitaires St-Luc
VilleBrussels
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