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This abstract is assigned to session FAB: Fluorescein Angiography Club Belgium
Presentation typeOB - oral
TitleFRO: Safety of the anterior vitreous detachment induced by microplasmin, pharmacologic vitreolysus to separate the posterior capsule from the anterior hyaloid
PurposeTo investigate the vitreolenticular interface and it's anomalies and to establish the safety of the use of microplasmin to promote the separation of the anterior hyaloids from the posterior capsule
MethodsPediatric cataract surgery using the bag-in-the-lens implantation technique was performed in 39 eyes of 30 children between September 2010 and August 2011. The age at time of surgery ranged from 1 month to 8 years old. Videoregistration was performed. Alterations in the vitreolenticular interface and the ease to separate the anterior hyaloids from the posterior capsule using viscoelastics were observed.
Remnants of posterior lens capsule, extracted out of the eye after performing posterior capsulorhexis, were fixated in Saccomanno’s fixative and sent for histologic examination to confirm the presence or indications of previous presence of hyaloidal adhesions to the centre of the posterior lens capsule. Some samples were fixated in gluteraldehyde solution and sent for electron microscopic evaluation, but were unfortunately all lost during processing. New imaging is planned for the end of September.
A study on rabbit eyes to establish the safety of the use of microplasmin at the vitreolenticular interface is planned for the near future.
Author 1
DepartmentUniversity Hospital Antwerp
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