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This abstract is assigned to session Poster session in O'Bistro
Presentation typeOB - poster
TitlePrevalence of glaucoma in patients with Graves' orbitopathy
Purpose1.To determine whether the elevation of IOP in patients with Graves' orbitopathy (GO) has an impact on onset of glaucomatous damage.
2.To assess the effects of orbital decompressing surgery on IOP.
MethodsRetrospective study including 153 eyes of 78 patients with GO. The records were studied and the patients were divided in the following groups: 1.GO with normal IOPs lower than 21 mmHg. 2.GO with OHT (IOP> 21 mmHg) without topical antiglaucomatouse meds. 3.GO with hypertension and topical treatment. Each patient underwent a complete examination on each visit including IOP in primary and up-gaze position, optic nerve examination and VF examination 30-2 using Humphrey sita-fast program.
Results56 female and 22 male were in total included in the study. The mean age was 51.9 ± 13.9 years (range 15 to 86 years). The mean Follow-up was 51.6 ± 13.2 months. 58,4% of the total GO had normal IOPs at baseline (16.6±3.6mmHg). 8.4% had raised IOP at baseline where no treatment was required (23.1± 1.3 mmHg). 31.8 % had raised IOP requiring topical meds (26.2 ±4.2 mmHg). In total, 27% of the included eyes had orbital decompression. De mean IOP preop was 20.9± 3.8 mmHg. The IOP on 1 month and 4 month Follow-up was respectively 18.8± 3.9 mmHg and 17.7± 3.4 mmHg. The mean IOP on the last follow-up was 16.1± 2.7. The drop in the IOP was statistically significant (p=0.001).
ConclusionThe elevated IOP in GO was found in more than 30% of the patients. It seems to be related to the compression of the eyeball and to the increased intraorbital pressure as result of the proliferation of the orbital adipose tissue and the enlargement as well as swelling of extraocular muscles. We have observed a significant reduction in IOP after decompression in our study sample.
Author 1
DepartmentClinques universitaires St. Luc, UCL
Author 2
DepartmentClinques universitaires St. Luc, UCL
Author 3
Last nameBOSCHI
DepartmentClinques universitaires St. Luc, UCL
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