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This abstract is assigned to session BOG-SBO 1 Medische retina/ Rétine médicale

Title	Primary Intravitreal Triamcinolone Acetonide for Diabetic Massive Macular Hard Exudates
Abstract Nr.	A1011

Purpose	To evaluate the efficacy of intravitreal triamcinolone acetonide (TA) as treatment for massive macular hard exudates in diabetic patients.
Methods	Prospective, noncomparative, interventional case series, of twelve eyes (12 patients) with massive hard exudates involving the fovea that had no previous focal laser treatment. A single intravitreal injection of 4 mg TA in 0.1 ml was performed. Visual acuity and evolution of hard exudates and fluorescein leakage were assessed. Potential complications were monitored, including ocular hypertension and endophthalmitis.
Results	Follow-up period ranged from 6 to 12 months (mean: 8.25 months). Mean visual acuity improved significantly from 20/300 to 20/160 (p = 0.039). Foveal hard exudates resolved completely in 6 eyes (50%) and partially in 6 eyes (50%). Fluorescein leakage decreased substantially in 11 eyes (91.7%) and moderately in one eye (8.3 %). A variable proportion of microaneurysms disappeared in all cases. An intraocular pressure elevation occurred in 3 eyes (25%), and was successfully treated by topical medication. No other complications, such as endophthalmitis, were recorded.
Conclusion	Intravitreal injection of TA appears to be beneficial for reducing hard exudates, decreasing fluorescein leakage, and improving significantly visual acuity in patients with diabetic massive hard exudates. Further studies are required to assess the long-term efficacy and safety, and the need for retreatment.

Author 1

Last name	Ben Yahia
Initials	S
Department	Ophthalmology, Fattouma Bourguiba University Hospital
City	Monastir

Author 2

Last name	Jelliti
Initials	B

Author 3

Last name	Zaouali
Initials	S

Author 4

Last name	Jenzeri
Initials	S

Author 5

Last name	Zaafouri
Initials	T

Author 6

Last name	Yazidi
Initials	B

Author 7

Last name	Chaieb
Initials	A

Author 8

Last name	Messaoud
Initials	R

Author 9

Last name	Ladjimi
Initials	A

Author 10

Last name	Khairallah
Initials	M
Department	Ophthalmology, Fattouma Bourguiba University Hospital
City	Monastir