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This abstract is assigned to session BOG-SBO 5 Neuro-oftalmologie / Neuro-ophtalmologie

Title	Non-Hodgkin lymphomas of the orbit and the ocular adnexa
Abstract Nr.	A2042

Purpose	Non-Hodgkin lymphomas (NHL) of the orbit and the ocular adnexa are rare. They represent approximately 10% of all orbital and extra-ocular tumours and only 1% of all systemic NHL. The most common type of NHL in the orbit is MALT (Mucosa Associated Lymphoid Tissue Lymphoma), a low-grade B-cell lymphoma, first described in the stomach by Isaacson and Wright in 1983. Extranodal low-grade lymphomas are sometimes difficult to distinguish from reactive lymphoid proliferations. Fluorescent in situ hybridisation (FISH) and polymerase chain reaction (PCR) which detect clonal rearrangements of the immunoglobulin heavy chain are necessary to demonstrate the neoplastic nature of the lymphoid cells.
Methods	We performed a retrospective analysis of the clinical and histopathological files of 68 patients, diagnosed with lymphoma or reactive lymphoid hyperplasia in the eye departement of the Ghent university hospital, between 1956 and 2003. All lymphoma were histologically reviewed and classified according to the World Health Organisation classification of hematopoetic tumors. Clinical and follow-up data were collected.
Results	The results of this study will be presented together with a review of the literature on reactive proliferations and NHL of the ocular adnexa

Author 1

Last name	RAEMDONCK
Initials	T
Department	Dept of Ophthalmology UZ
City	Ghent

Author 2

Last name	DE PAEPE
Initials	P
Department	Dept of Pathology UZ
City	Ghent

Author 3

Last name	VAN DEN BROECKE
Initials	C
Department	Dept of Pathology UZ
City	Ghent

Author 4

Last name	KESTELYN
Initials	Ph
Department	Dept of Opthalmology UZ
City	Ghent