View abstract

This abstract is assigned to session Poster session in O'Bistro

Title

Long Follow Up of Juvenile Idiopathic Arthritis Associated Uveitis

Purpose	To evaluate treatment and outcome of patients with juvenile idiopathic arthritis (JIA)-associated uveitis.
Methods	Retrospective chart review of 18 cases (aged between 1 and 16 years at diagnosis) of JIA associated uveitis. Collected data was: gender, age at diagnosis (uveitis and arthritis), follow up duration, arthritis subtype, ANA positivity, treatment, complications and visual acuity (initial and final).
Results	Eighteen patients (14 F) were included, 11 with oligoarticular subtype, 12 positive for ANA. Mean age of JIA related arthritis, uveitis and at end follow up were respectively 3.13, 3.9 and 19 years. Mean follow up duration was 10.6 years. All had systemic steroids. Fifteen patients took immunomodulatory drugs, 11 took anti-TNF alpha. Eight patients had a final VA <20/40 at least in 1 eye. Cataract was noted in all but 2 patients. Elevated IOP occurred in 14 and hypotony in 7 cases. Retina detached in 4 patients. Inactivity was noted in 10 patients with ongoing immunomodulatory drugs and in 3 with only topical steroids at the last follow up. Steroid side effects were potentially reversible.
Conclusion	JIA associated uveitis treatment remains challenging, ocular morbidity lasting well into adulthood. Drug associations were useful to decrease dosage and severe drug-related side effects.

Authors 1

Last name	LEYS
Initials	E
Department	CHU Saint-Pierre
City	Brussels

Authors 2

Last name	BALIKOVA
Initials	I
Department	CHU Saint-Pierre - HUDERF
City	Brussels

Authors 3

Last name	VAN BOL
Initials	L
Department	Erasme
City	Brussels

Authors 4

Last name	JANSSENS
Initials	X
Department	CHU Saint-Pierre
City	Brussels

Authors 5

Last name	PASTEELS
Initials	B
Department	CHU Brugmann
City	Brussels

Authors 6

Last name	CARION
Initials	T
City	Verviers

Authors 7

Last name	WILLERMAIN
Initials	F
Department	CHU Saint-Pierre
City	Brussels

Authors 8

Last name	FERSTER
Initials	A
Department	HUDERF
City	Brussels

Authors 9

Last name	LÊ
Initials	PQ
Department	HUDERF
City	Brussels

Authors 10

Last name	CASPERS
Initials	L
Department	CHU Saint-Pierre
City	Brussels