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Title

Long-term results of low-fluence photodynamic therapy in chronic central serous chorioretinopahy

Purpose	To evaluate long-term results of low-fluence photodynamic therapy (PDT) with verteporfin in the treatment of Chronic Central Serous Chorioretinopathy (CCSC).
Methods	Retrospective medical record review of 42 eyes (39 patients) who received low-fluence PDT for the treatment of CCSC. Visual acuity, fundus biomicroscopy, fluorescein angiography (FA), indocyanine green angiography (ICG) and optical coherence tomography (OCT) were analysed.
Results	Forty two eyes (39 patients) with CCSC received low fluence PDT. Mean follow-up after PDT was longer than 3 years (39,43 months; range, 12-96 months; median, 36 months). Mean logMar best corrected visual acuity (BCVA) improved significantly from 0,32 (0,48 Snellen visual acuity) to 0,1 (0,80 Snellen visual acuity) at the last follow up which corresponds to a gain of 2,2 lines in logMar scale. Complete resolution of central subretinal fluid on OCT was achieved 6 months after 1 PDT in 41 eyes and after 2 PDTs in 1 eye (treated at 3 months after first PDT). No treatment-related side effects were observed.
Conclusion	Low fluence PDT for CCSC is efficient and safe at long term.

Authors 1

Last name	LEYS
Initials	E
Department	CHU Brugmann - CHU Saint-Pierre
City	Brussels

Authors 2

Last name	TUTTLE
Initials	S
Department	CHU Brugmann
City	Brussels

Authors 3

Last name	RASQUIN
Initials	F
Department	Erasme
City	Brussels

Authors 4

Last name	NEU
Initials	F
Department	Erasme
City	Brussels

Authors 5

Last name	POSTELMANS
Initials	L
Department	CHU Brugmann
City	Brussels