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This abstract is assigned to session BOG-SBO 1 Medische retina/ Rétine médicale
TitlePhotodynamic treatment of circumscribed choroidal hemangiomas
Abstract Nr.A1009
PurposeTo evaluate the safety and efficacy of photodynamic therapy (PDT) in the treatment of symptomatic circumscribed choroidal hemangiomas (CCH).
MethodsThis prospective nonrandomized study included 8 patients referred to us for management of CCH with exudative activity. PDT was applied by diode laser (689nm) with a light dose of 50 J/cm² and using verteporfin (6 mg/m²) IV bolus injection. The treatment spot diameter was related to the tumor basal diameter (TBD).
ResultsThe mean tumor thickness before PDT was 3.3 mm and the mean largest TBD was 6.9 mm . All patients were managed with a single PDT application. After a mean follow-up of 12 months, all CCH (100%) showed regression of the vascular tumor mass with a final tumor thickness of 2.3 mm and complete resorption of the serous retinal fluid (SRF). All CCH showed overlying PDT–related RPE atrophic changes. No cases of retinal vascular occlusion or recurrent leakage was documented. Six patients (75%) had visual improvement, one (12.5%) had stable vision and one (12.5%) had worse vision due to chronic exudation-related RPE changes.
ConclusionPDT using verteporfin offers a safe and effective option to treat CCH. Complete resorption of the subretinal fluid is associated with visual improvement.
Author 1
Last nameGUAGNINI
InitialsAP
DepartmentOcular Oncology Unit, Cliniques Universitaires St-Luc
CityBrussels
Author 2
Last nameDE POTTER
InitialsP
DepartmentOcular Oncology Unit, Cliniques Universitaires St-Luc
CityBrussels
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