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Title	Emulsification of silicone oil and F4H5 to capture oil droplets
Abstract Nr.	P129

Purpose	Emulsification is a well-known and frequent problem when silicone oil is used during vitrectomy. Formation of small oil droplets occurs, causing inflammation and elevated intra-ocular pressure. Emulsification occurs less in 5000 cs silicone oil than in 1000 cs, but the former is more difficult to handle and has less tamponading effect on the retina. A new silicone oil is available (Siluron 2000) which has in vitro properties to combined the advantages of both silicone oil types. Wash of the vitreous cavity and anterior chamber with F4H5 has been proposed to capture oil droplets at the time of silicone oil removal.
Methods	In a prospective, randomized clinical trial, 72 patients were randomized for either Siluron 2000 or 5000 silicone oil. After 3 months, the silicone oil was removed and collected to analyse the amount of emulsification. In 50% of the patients in each study arm, a wash of the vitreous cavity with F4H5 was performed. After 6 weeks, a B-scan ultrasound was performed with automated counting of remaining oil droplets to determine the effect of this F4H5 wash. Moreover, gonioscopy was used to assess the amount of emulsification in the anterior chamber.
Results	For all clinical parameters analysed, there was no difference between the 2000 and 5000 study arm. Although the ultrasound measurement was not different in the F4H5 study arm, there was a significantly reduced number of silicone oil bubbles found in the anterior chamber.
Conclusion	1. In daily surgical practice, Siluron 2000 silicone oil is non-inferior to Siluron 5000, but handles significantly easier during surgery. 2. A wash using F4H5 significantly reduces the amount of emulsification found in the anterior chamber.

Authors 1

Last name	STALMANS
Initials	P
Department	UZ Leuven, Ophthalmology
City	Leuven