Titre | Characteristics and prognostic factors in conjunctival melanoma |
Abstract Nr. | 1056 |
But | To investigate the different characteristics and prognostic factors in 45 conjunctival melanomas. Risk factors for local recurrence and regional and distant metastases and overall survival were analysed. |
Méthodes | Retrospective study. |
Résultats | Retrospectively 45 patients (30 males, 15 females) with conjunctival melanoma were identified in the last 15 years. Mean age at first diagnosis was 62.5 years. In 18 patients Strontium brachytherapy and in 7 Iridium brachytherapy was used. The mean number of recurrences (both at the same place and at another location of the conjunctiva) was 2 (range 1-6) within the mean follow-up time of 4.5 years. In 9 patients regional metastases developed and in 9 distant metastases. Multilocality and tumor thickness are significant prognostic factors. |
Conclusion | Nonepibulbar tumors more often recur locally and are associated with a shorter survival independent of other risk factors. Tumor thickness is also an important predictor in conjunctival melanoma. In many cases conjunctival melanoma behaves as a chronic disease. |
Nom | FABRY |
Initiales | A |
Institut | UZ Leuven |
Ville | Leuven |
Nom | Van Ginderdeuren |
Initiales | R |
Institut | UZ Leuven |
Ville | Leuven |
Nom | Spileers |
Initiales | W |
Institut | UZ Leuven |
Ville | Leuven |
Nom | Missotten |
Initiales | G |
Institut | UZ Leuven |
Ville | Leuven |