Titre | Effect of dexamethasone intravitreal implant in the treatment of noninfectious uveitis |
Abstract Nr. | 2039 |
But | To investigate the effect of dexamethasone intravitreal implant (Ozurdex; Allergan, Inc) in noninfectious uveitis. |
Méthodes | Charts of patients with noninfectious uveitis treated by dexamethasone intravitreal implants were reviewed in a retrospective study. Uveitis etiologies, treatment indications, visual acuity, central retinal thickness measured by optical coherence tomography, intraocular pressure, number of injections were collected. Parameters were analyzed before injection, after 5-6 weeks (short follow-up) and 4-5 months (long follow-up) post-Ozurdex injection. |
Résultats | We included 14 patients (20 eyes, 26 implants injections). Before injections, mean visual acuity was 0.4±0.5 logMAR and improved to 0.3±0.5 logMAR at short time follow-up and to 0.3±0.5 logMAR at long time follow-up. Macular thickness has decreased by 81.4±99.4 µm at short time follow-up and 61.3±139.5 µm at long time follow-up. Mean intraocular pressure was 16±5 mmHg before injections, 18±6 mmHg at short time follow-up and 14±3 mmHg at long time follow-up. |
Conclusion | In noninfectious uveitis, dexamethasone implant can improve visual acuity and decrease macular thickness without significant increase of intraocular pressure. Although the effect seems limited in time. |
Nom | FRERE |
Initiales | A |
Institut | CHU Saint-Pierre and CHU Brugmann |
Ville | Brussels |
Nom | Janssens |
Initiales | X |
Institut | CHU Saint-Pierre |
Ville | Brussels |
Nom | Makhoul |
Initiales | D |
Institut | CHU Saint-Pierre and CHU Brugmann |
Ville | Brussels |
Nom | Judice |
Initiales | l |
Institut | CHU Saint-Pierre and CHU Brugmann |
Ville | Brussels |
Nom | Postelmans |
Initiales | L |
Institut | CHU Brugmann |
Ville | Brussels |
Nom | Lefebvre |
Initiales | P |
Institut | CHU Saint-Pierre |
Ville | Brussels |
Nom | Caspers |
Initiales | L |
Institut | CHU Saint-Pierre |
Ville | Brussels |
Nom | Mélot |
Initiales | C |
Institut | Erasme Academic Hospital |
Ville | Brussels |
Nom | Willermain |
Initiales | F |
Institut | CHU Saint-Pierre |
Ville | Brussels |