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This abstract is assigned to session AOB and FRO E-Posters

Title	Merkel Cell Carcinoma with locoregional and distant spread
Abstract Nr.	3021

Purpose	Merkel cell carcinoma (MCC) of the eyelid is a rare disease. Nonocular MCC is known to recur in 66% and to be lethal in almost 33%. In a previous study (Ophthalmology 2008; 115: 195-201), reviewing 86 patients with eyelid MCC, only 2 patients died of distant metastasis of eyelid MCC. Here, we review 6 cases of the last 5 years with MCC.
Methods	Case description and literature review.
Results	Two of the 6 new cases showed locoregional spread, and one patient developed distant metastasis within two years of the primary diagnosis of eyelid MCC. We discuss the need of locoregional biopsies, in view of the larger literature.
Conclusion	Distant metastases of eyelid MCC are less frequent than metastases of nonocular MCC, probably due to early diagnosis. Eyelid MCC larger than 2 cm, may justify locoregional surgery/biopsy.
Conflict of interest	No

Authors 1

Last name	VAN AERSCHOT
Initials	J
Department	UZLeuven, Department of ophthalmology
City	Leuven

Authors 2

Last name	VAN GINDERDEUREN
Initials	R
Department	UZLeuven, Department of ophthalmology
City	Leuven

Authors 3

Last name	MISSOTTEN
Initials	G
Department	UZLeuven, Department of ophthalmology
City	Leuven