THE BELGIAN OPHTHALMIC ASSOCIATIONS
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This abstract is assigned to session Ped & Low - Pediatric Ophthalmology and Low-Vision
| Title | Ocular side effects of Vigabatrin in children |
| Abstract Nr. | 1079 |
| Purpose | Vigabatrin is an inhibitor of GABA transaminase used for the treatment of infantile spasms and epilepsy refractory to others treatments. Unfortunately, it can be associated with permanent peripheral visual field defects that are difficult to detect in young patients. The purpose is to update the recommended ophthalmologic follow up of children taking Vigabatrin. |
| Methods | A literature review of visual loss related to Vigabatrin is presented. The screening tests, such as ophthalmoscopy, automated visual fields, SD OCT, ERG, VEP, will be reviewed. |
| Results | Epileptic patients may have visual defects not attributed to Vigabatrin. In non-verbal, uncooperative young patients, ophthalmoscopy is recommended at baseline and every 3 months |
| Conclusion | Periodic dilated ophthalmoscopy is the best method to avoid unnecessary cessation of this valuable medication in epileptic young patient. |
| Conflict of interest | No |
Authors 1
| Last name | YOUSSFI |
| Initials | AY |
| Department | Hôpital Erasme |
| City | Bruxelles |