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TitleCorneal ectasia caused by Vitamin C deficiency
PurposeIn this case series we discuss three patients with a progressive corneal ectasia and a proven vitamin C deficiency.
MethodsCase series
ResultsThree patient presented with atypical features of corneal ectasia. Two out of three were above 40 years old and they all had a peculiar general history. The first patient, who is a twenty eight year old female does not eat any raw vegetables and nuts due to allergy. The second patient is a forty year old man with a history of a laparoscopic sleeve gastrectomy and cholecystectomy. The third patients is a forty-eight year old female with Morbus Crohn who had a hemicolectomy when she was 25 years old. They all came to our department because of decreased visual acuity. Corneal tomography by Scheimpflugh imaging (Pentacam) showed in all three cases an irregular astigmatism, congruent with some type of ectasia. A blood sample was taken and a vitamin C deficiency was diagnosed.
ConclusionTo the best of our knowledge, we are the first to present a possible correlation between corneal ectasia and vitamin C deficiency. Although more research is needed, it can be interesting to determine the vitamin C plasma levels in a patient presenting with an atypical ectasia. When a vitamin C deficiency is confirmed, it should be substituted orally.
Conflict of interestNo
Details of conflicting interestsThe authors declare no conflict of interest
Authors 1
Last nameCLIJSTERS
InitialsLC
DepartmentUZ Leuven
CityLeuven
Authors 2
Last nameDELBEKE
InitialsHD
DepartmentUZ Leuven
CityLeuven
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