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This abstract is assigned to session OB Poster session > in O'Bistro

Title

Juvenile xanthogranuloma of the corneoscleral limbus

Purpose	To report the clinical and histopathologic findings of limbal juvenile xanthogranuloma (JXG) in two children.
Methods	Two case reports with slit-lamp photography and histopathological examination.
Results	Two children (a 9-month old boy and a 4-year old girl) presented with an enlarging yellowish mass at the corneoscleral limbus. The girl had been diagnosed with neurofibromatosis 1 (NF1). Both lesions underwent simple excision. Histopathologic examination revealed foamy histiocytes within an inflammatory infiltrate with the presence of multiple multinucleated giant cells. In both cases intraoperative subconjunctival steroids and postoperative topical steroids were administered during one month.
Conclusion	Juvenile xanthogranuloma may rarely present as a mass occurring at the corneoscleral limbus. Therefore it should be considered in the differential diagnosis of any corneoscleral limbal mass lesion, particularly in children. Most are isolated lesions without systemic involvement which are treated by simple excision. Here we report on an isolated case and a case of a limbal xanthogranuloma associated with neurofibromatosis type 1. Both were treated by simple excision and showed no recurrence after 9 months.

Author 1

Last name	DE KEYSER
Initials	C
Department	UZ Leuven
City	Leuven

Author 2

Last name	Maudgal
Initials	P
Department	UZ Leuven
City	Leuven

Author 3

Last name	Legius
Initials	E
Department	UZ Leuven
City	Leuven

Author 4

Last name	Vanginderdeuren
Initials	R
Department	UZ Leuven
City	Leuven

Author 5

Last name	Casteels
Initials	I
Department	UZ Leuven
City	Leuven