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This abstract is assigned to session OB Poster session > in O'Bistro

Title

Radiation-induced optic neuropathy: is the diagnosis really that easy?

Purpose	To discuss the difficulty in making the differential diagnosis of a thickened optic chiasm and optic nerve in a patient who received radiotherapy for a temporal lobe astrocytoma.
Methods	Case report
Results	The case of a 46-year old woman is presented with bilateral visual loss. In the medical history she had a resection of an anaplastic astrocytoma WHO grade III on the right temporal lobe in oktober 2008, followed by radiotherapy and chemotherapy. The vision deteriorated very fast in both eyes to 4/20 with a left homonimous hemianopsia. MRI scan showed a thickened optic chiasm and diffuse enhancement of the optic nerves Differential diagnosis as well as possible therapeutic strategies are discussed.
Conclusion	The diagnosis of radiation-induced optic neuropathy can only be confirmed when all other possibilities are excluded.

Author 1

Last name	DE KEYZER
Initials	THW
Department	Department of Ophthalmology, University Hospital
City	Antwerp

Author 2

Last name	de Keizer
Initials	RJW
Department	Department of Ophthalmology, University Hospital
City	Antwerp

Author 3

Last name	Menovsky
Initials	T
Department	Department of Neurosurgery, University Hospital
City	Antwerp

Author 4

Last name	Parizel
Initials	P
Department	Department of Radiology, University Hospital
City	Antwerp