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Deze abstract is toegekend aan sessie OB Free papers 4 - Glaucoma
Titel24 hour-intraocular pressure fluctuation monitoring using an ocular telemetry Sensor: functionality and tolerability in healthy subjects
DoelTo evaluate the precision of the signal transmission, the tolerability and comfort of an ocular Sensor used for 24-hour intraocular pressure fluctuation monitoring in humans.
MethodesIn this uncontrolled open trial involving 10 healthy volunteers an 8.7 mm radius prototype ocular telemetry Sensor (SENSIMED Triggerfish®, Lausanne, Switzerland) and an orbital bandage containing a loop antenna were applied and connected to a portable recorder after full eye examination. Best corrected visual acuity and position, surface wetting ability and mobility of the Sensor were assessed after 5 and 30 minutes, 4, 12 and 24 hours. Subjective wearing comfort was scored and activities documented in a logbook. After Sensor removal a full eye examination was repeated and the recorded signal analyzed.
ResultatenThe comfort score was high and did not fluctuate significantly over time. The mobility of the Sensor was limited across follow-up visits and its surface wetting ability remained good. Best corrected visual acuity was significantly reduced during Sensor wear and immediately after its removal (from 1.07 before, to 0.85 after, P-value 0.008). Three subjects developed a mild, transient corneal abrasion. In all but one participant we obtained usable data of a telemetric signal recording with sufficient sensitivity to depict ocular pulsation.
ConclusieThis 24 hour-trial confirmed the functionality and tolerability of the ocular telemetric Sensor for intraocular pressure fluctuation monitoring in human volunteers. Further studies conducted with different Sensor radii as well as trials to improve the interpretation of the telemetric signal are indicated.
Auteur 1
NaamDE SMEDT
InitialenS
InstituutGlaucoma Center at the Montchoisi Clinic
Stad Lausanne
Auteur 2
NaamMermoud
InitialenA
InstituutGlaucoma Center at the Montchoisi Clinic
Stad Lausanne
Auteur 3
NaamSchnyder
InitialenC
InstituutJules Gonin Eye Hospital
StadLausanne
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