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TitelJuvenile xanthogranuloma of the corneoscleral limbus
DoelTo report the clinical and histopathologic findings of limbal juvenile xanthogranuloma (JXG) in two children.
MethodesTwo case reports with slit-lamp photography and histopathological examination.
ResultatenTwo children (a 9-month old boy and a 4-year old girl) presented with an enlarging yellowish mass at the corneoscleral limbus. The girl had been diagnosed with neurofibromatosis 1 (NF1). Both lesions underwent simple excision. Histopathologic examination revealed foamy histiocytes within an inflammatory infiltrate with the presence of multiple multinucleated giant cells. In both cases intraoperative subconjunctival steroids and postoperative topical steroids were administered during one month.
ConclusieJuvenile xanthogranuloma may rarely present as a mass occurring at the corneoscleral limbus. Therefore it should be considered in the differential diagnosis of any corneoscleral limbal mass lesion, particularly in children. Most are isolated lesions without systemic involvement which are treated by simple excision. Here we report on an isolated case and a case of a limbal xanthogranuloma associated with neurofibromatosis type 1. Both were treated by simple excision and showed no recurrence after 9 months.
Auteur 1
NaamDE KEYSER
InitialenC
InstituutUZ Leuven
StadLeuven
Auteur 2
NaamMaudgal
InitialenP
InstituutUZ Leuven
StadLeuven
Auteur 3
NaamLegius
InitialenE
InstituutUZ Leuven
StadLeuven
Auteur 4
NaamVanginderdeuren
InitialenR
InstituutUZ Leuven
StadLeuven
Auteur 5
NaamCasteels
InitialenI
InstituutUZ Leuven
StadLeuven
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