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TitelContributiuon of spectral-domain optical coherence tomography in a case of familial occult macular dystrophy.
DoelTo document the interest of using spectral-domain optical coherence tomography (SD-OCT) for the diagnosis and for the comprehension of macular dysfunction in occult macular dystrophy (OMD).
MethodesOMD is characterized by a progressive decline of visual acuity with normal fundus, normal fundus auto-fluorescence and normal fluo-angiography. In this clinical context, abnormal mf-ERG remains until now the gold standard to allow the diagnosis of OMD. However, SD-OCT may demonstrate significant anatomic changes in the photoreceptors layer. Morphologic photoreceptors layer abnormalities were investigated with SD-OCT in a member of a family with OMD.
ResultatenThe SD-OCT demonstrated a foveal well-defined disruption of the inner segment-outer segment junction of photoreceptors.
ConclusieOMD is a rare macular disorder which is very difficult to diagnose. The diagnosis can be promoted by using SD-OCT, demonstrating a disruption of the photoreceptors layer. These OCT findings most probably participate in the pathophysiology of vision lowering associated with OMD.
Auteur 1
NaamPIENS
InitialenI
Instituuthopital erasme
Stadbruxelles
Auteur 2
NaamCORDONNIER
InitialenM
Instituuthopital erasme
Stadbruxelles
Auteur 3
NaamRASQUIN
InitialenF
Instituuthopital erasme
Stadbruxelles
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