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Cet abstract a été assigné à session OB Free papers 2 - Surgical retina
TitreOxymap: a novel tool to measure retinal oxygenation
ButDisturbances in retinal blood flow and oxygenation are involved in several ophtalmologic diseases . Those include some of the more common eye diseases such as retinal vascular occlusions, glaucoma and diabetic retinopathy.
Studies suggest that some treatments, such as laser photocoagulation and vitrectomy, may improve retinal oxygenation. Hence, we wanted to evaluate if enzymatic detachment of the posterior hyaloid could also influence the retinal oxygenation.
MéthodesPatients with adherent hyaloid were included in an open label phase II clinical trial (MIVI-008, 30 patients scheduled). In all patients, a retinal oxymetry was performed at baseline and at six months. Additionally, we screened patients scheduled for macular hole surgery (and adherent posterior hyaloid) with retinal oxymetry before and after surgery.
RésultatsRecently, it has been demonstrated in a phase 3 trial that a complete detachment of the hyaloid can be obtained in almost 15% of patients after one month. The resulting change in retinal oxygenation will be measured and compared to the effect documented after vitrectomy.

ConclusionThe Oxymap is a novel diagnostic tool to perform retinal oxymetry in a non-invasive way. Our study will determine the effect of detachment of posterior hyaloid (enzymatic versus surgical) on the retinal oxygenation
Auteur 1
NomJANSEN
InitialesJ
InstitutUniversity hospitals
VilleLeuven
Auteur 2
NomDEGHISLAGE
InitialesC
InstitutUniversity hospitals
VilleLeuven
Auteur 3
NomVAN CALSTER
InitialesJ
InstitutUniversity hospitals
VilleLeuven
Auteur 4
NomSTALMANS
InitialesP
InstitutUniversity Hospitals
VilleLeuven
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