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Presentation type	E-poster
Title	Anaphylactic shock following cataract surgery: a documented intracameral cefuroxime allergy

Purpose	To report a documented life-threatening immediate hypersensitivity reaction to intracameral administration of cefuroxime after cataract surgery
Methods	An 81-year-old woman underwent phacoemulsification under topical anesthesia. At the end of the intervention, she developped a severe anaphylactic reaction and lost consciousness. She was immediately managed by the anesthetist and then admitted to the intensive care unit. An anaphylactic shock due to a substance received during the cataract surgery was suspected. Four months later, diagnostic skin prick-tests (SPT) were performed with all the medications used during surgery.
Results	Ten minutes after SPT with cefuroxime, dyspnea, palmar pruritus, oedema of the lips appeared. The blood pressure fell to 80/40 mmHg. Intravascular filling, intravenous adrenalin, glucocorticoids were immediately administered and the patient's condition improved quickly. SPT were positive for cefuroxime and negative for all other molecules. The result of SPT provided convincing evidence the cefuroxime was the causal agent.
Conclusion	This case could increase the awareness that perioperative anaphylactic reactions are sometimes not predictable and can occur during surgeries under topical anaesthesia. The presence of an anesthetist is useful to manage such life threatening complications.
Conflict of interest	No

Authors 1

Last name	LEVECQ
Initials	L
Department	Ophthalmology department, CHU UCL Namur, Université catholique de Louvain
City	Yvoir

Authors 2

Last name	SCHMIT
Initials	P
Department	Ophthalmology department, CHU UCL Namur, Université catholique de Louvain
City	Yvoir

Authors 3

Last name	MAHIAT
Initials	C
Department	Pneumology department, CHU UCL Namur, Université catholique de Louvain
City	Yvoir

Authors 4

Last name	ROBAYE
Initials	S
Department	Anesthesiology department, CHU UCL Namur, Université catholique de Louvain
City	Yvoir

Authors 5

Last name	SOHY
Initials	C
Department	Pneumology department, CHU UCL Namur, Université catholique de Louvain
City	Yvoir