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Presentation type	E-poster
Title	[ RECORDED ] Subconjunctival venous malformation with progressive hemorrhage in a child with the blue rubber bleb nevus (BRBNS) syndrome on treatment with oral propranolol

Purpose	To report the first case in literature of a child with the BRBNS with a subconjunctival venous malformation with progressive hemorrhage necessitating topical treatment in addition to oral propranolol.
Methods	Case report and literature review on PubMed by choosing the following MeSH terms: blue rubber bleb nevus syndrome- eye-treatment.
Results	A 3-year-old boy with BRBNS on treatment with oral propranolol, presented at our emergency department with a subconjunctival hemorrhage in the left eye. Mother noticed a small red punctiform lesion ten days before, suggestive of a new vascular lesion. At first, no additional treatment to the oral propranolol was initiated but 3 days later he was urgently referred because of a progressive subconjunctival hemorrhage. Topical treatment with timolol maleate 0.5% once a day was started. After 2 weeks, there was progressive resorption of the hemorrhage with complete clearance after 2 months. Topical treatment was stopped after 6 months and after 1 year of follow-up, there has been no relapse.
Conclusion	We published the first child with BRBNS and a subconjunctival venous malformation and progressive hemorrhage necessitating topical treatment in addition to oral propranolol. For patients with BRBNS-related subconjunctival vascular lesions, treatment with a topical β-blocker may be an efficient and harmless treatment option.
Conflict of interest	No

Authors 1

Last name	DE LOECKER
Initials	K
Department	Department Ophthalmology, University Hospitals Leuven
City	Leuven

Authors 2

Last name	LABARQUE
Initials	V
Department	Department Paediatric Haematology, University Hospitals Leuven
City	Leuven

Authors 3

Last name	SEYNAEVE
Initials	H
Department	Department Ophthalmology, AZ Delta Roeselare
City	Roeselare

Authors 4

Last name	CASTEELS
Initials	I
Department	Department Ophthalmology, University Hospitals Leuven
City	Leuven