| Titre | Functional and structural ophthalmological outcome in cryo- or lasertreated premature babies with retinopathy of prematurity (ROP) between 1989 and 2008 |
| But | To assess the evolution in postmenstrual age (PMA) at birth, birth weight, PMA at treatment, visual outcome, ophthalmoscopic appearance, refractive errors and strabismus in infants treated for ROP between 1989 and 2008 at the University Hospitals of Leuven, Belgium. |
| Méthodes | Retrospective analysis of the medical records of premature infants with ROP who were treated with cryotherapy or lasertherapy. The study population is divided into three groups. In group 1 (1989-1995) 26 cryo treated infants and in group 2 (1996-1999) 32 cryo treated infants are included. Group 1 was treated at the threshold stage whereas group 2 was treated at the prethreshold stage. Group 3 consists of 37 laser treated infants (2002-2008). Infants treated during the transition time from cryotherapy to lasertherapy (1999 - 2001) were excluded. |
| Résultats | Between the three groups differences in mean PMA at birth, mean birth weight and mean PMA at treatment were evaluated. Visual and refractive outcome, ophthalmoscopic appearance were compared. The presence of strabismus within the three groups, and involvement of the central nervous system were evaluated. |
| Conclusion | There is a tendency to better ophthalmological functional and structural outcome in infants treated with cryotherapy at the prethreshold stage (group 2) compared to those who were treated at the threshold stage (group 1). Ophthalmological functional and structural outcome is better in infants treated with lasertherapy (group 3) compared to those treated with cryotherapy (group 1 and 2). Subanalysis of the more recently laser treated group shows that poor visual outcome can mainly be attributed to central nervous system involvement. High myopia is mainly present in children who were diagnosed with ROP rush disease. |
| Nom | CASSIMAN |
| Initiales | C |
| Ville | Leuven |
| Nom | Stalmans |
| Initiales | P |
| Ville | Leuven |
| Nom | Van Calster |
| Initiales | J |
| Ville | Leuven |
| Nom | Allegaert |
| Initiales | K |
| Ville | Leuven |
| Nom | Casteels |
| Initiales | I |
| Ville | Leuven |