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This abstract is assigned to session OB Free papers 2 - Surgical retina

Title

Oxymap: a novel tool to measure retinal oxygenation

Purpose	Disturbances in retinal blood flow and oxygenation are involved in several ophtalmologic diseases . Those include some of the more common eye diseases such as retinal vascular occlusions, glaucoma and diabetic retinopathy. Studies suggest that some treatments, such as laser photocoagulation and vitrectomy, may improve retinal oxygenation. Hence, we wanted to evaluate if enzymatic detachment of the posterior hyaloid could also influence the retinal oxygenation.
Methods	Patients with adherent hyaloid were included in an open label phase II clinical trial (MIVI-008, 30 patients scheduled). In all patients, a retinal oxymetry was performed at baseline and at six months. Additionally, we screened patients scheduled for macular hole surgery (and adherent posterior hyaloid) with retinal oxymetry before and after surgery.
Results	Recently, it has been demonstrated in a phase 3 trial that a complete detachment of the hyaloid can be obtained in almost 15% of patients after one month. The resulting change in retinal oxygenation will be measured and compared to the effect documented after vitrectomy.
Conclusion	The Oxymap is a novel diagnostic tool to perform retinal oxymetry in a non-invasive way. Our study will determine the effect of detachment of posterior hyaloid (enzymatic versus surgical) on the retinal oxygenation

Author 1

Last name	JANSEN
Initials	J
Department	University hospitals
City	Leuven

Author 2

Last name	DEGHISLAGE
Initials	C
Department	University hospitals
City	Leuven

Author 3

Last name	VAN CALSTER
Initials	J
Department	University hospitals
City	Leuven

Author 4

Last name	STALMANS
Initials	P
Department	University Hospitals
City	Leuven