Abstract bekijken

Deze abstract is toegekend aan sessie AOB Poster session1
TitelClinical trial of Ultrasonic Circular Cyclo Coagulation in patients with open angle glaucoma.
Abstract Nr.1033
DoelTo evaluate the relative safety and the potential efficacy of the ultrasound circular cyclo coagulation (UC3 ) treatment in patients with open angle glaucoma (GCAO).
MethodesA miniaturized high-intensity focused ultrasound with six piezoelectric transducers (HIFU) was used to insonify 23 eyes in 20 patients. The patient inclusion criteria were male or female at least 18 years old, with GCAO refractory to medical treatment and selective laser therapy. The first series comprised 10 patients (12 eyes) with a follow-up (FU) of 6 months, the second series included 10 patients (11 eyes) with a FU of 3 months. The study comprised a complete ophthalmic examination with intra-ocular pressure (IOP) measurements before the procedure, at 15 days, 1 month, 2 months, 3 months and 6 months after the procedure.
ResultatenIn the first series, the 6 months’ results show a decrease in IOP from a mean preoperative value of 25.39±5.62mmHg to a mean value of 15.87±3.04mmHg (n=8, p<0.001). The second series show a decreased of IOP from 19.7±3.97 mmHg to 14.75±4.35 mmHg at 2 months (n=10, p<0.001) and to 15.25±6.40mmHg at 3 months (n=5, p=0.05). 5 patients (n=5) had to undergo in the meanwhile other procedures to maintain their target pressure and therefore were not included in the statistical analysis. No major complications intra- or postoperative occurred except in the two patients with hypertonic uveitis. Indeed, we observed in those cases an increase of the intracameral inflammation (n=2) and a macular cystoid edema (n=1).
ConclusieUC3 reduce IOP by destroying the ciliary processes in the majority of the patients but seems to be less effective in patients with hypertonic uveitis.
Auteur 1
NaamCHAPELLE
InitialenAC
InstituutCHU Sart-Tilman
StadLiège
Auteur 2
NaamDUPONT
InitialenG
InstituutCHU Sart-Tilman
StadLiège
Auteur 3
NaamCOLLIGNON
InitialenNJ
InstituutCHU Sart-Tilman
StadLiège
top ^