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This abstract is assigned to session AOB and FRO E-Posters

Title	Collagen crosslinking as a treatment for corneal hydrops in ectatic disorders
Abstract Nr.	3032

Purpose	To report a small case series of collagen crosslinking (CXL) as a treatment for corneal hydrops in ectatic disorders.
Methods	Retrospective chart review of 2 cases of corneal hydrops treated with CXL. Work-up included basic ophthalmological examination, slit lamp photography, pachymetry and corneal tomography. Both patients underwent CXL according to the Dresden protocol.
Results	A 23-year old man with bilateral keratoconus presented with acute corneal hydrops in the left eye. Topical treatment was started, however 8 weeks after presentation our patient complained of persisting ocular discomfort. CXL was performed and already after 1 week ocular discomfort and redness decreased. After 2 weeks a reduction of stromal edema was noticed. Corneal thickness remained stable up to 2 years after CXL, when our patient underwent penetrating keratoplasty (PK). Secondly, a 43-year old woman with bilateral keratoglobus presented with acute corneal hydrops in the right eye. Despite topical treatment, ocular discomfort and stromal edema persisted up to 8 weeks after presentation. CXL was performed, after which stromal edema decreased and corneal thinning stabilized. 1 year after CXL she underwent combined PK and cataract surgery.
Conclusion	Our results suggest that collagen CXL decreases ocular discomfort and stromal edema in corneal hydrops. CXL can be offered to patients when other conservative treatments have failed. After stabilization of corneal thinning keratoplasty can be perfomed to restore visual function.
Conflict of interest	No

Authors 1

Last name	ROELS
Initials	D
Department	Dpt of Ophthalmology, Ghent University Hospital
City	Ghent, Belgium

Authors 2

Last name	Geerards
Initials	AJM
Department	Dpt of Ophthalmology, The Rotterdam Eye Hospital
City	Rotterdam, The Netherlands