Title | Mesectodermal leiomyoma: current diagnostic approach and management |
Purpose | Mesectodermal leiomyoma is a rare benign intraocular tumor, on which mostly only single case reports (nr:~60), based on coincidental histopathological findings, have been published. Clear diagnostic or therapeutic guidelines have not been published yet. |
Methods | We studied retrospectively 5 consecutive leiomyoma cases, observed or treated since 2001. We present their clinical features, differential diagnostic approach, and management. |
Results | Referral diagnosis of all cases was uveal melanoma. All tumors were well delineated and originated in the ciliary body (4) or anterior choroid (1). Median thickness was 7.6 mm (4.0-12.6), with low internal reflectivity and a supraciliary/-choroidal location on US examination (UBM/20/10 MHz). Suspicion of leiomyoma (4) or melanocytoma (1) had motivated incisional biopsy as a diagnostic approach. Management consisted of specific surgical incision (3) or periodic observation (2). |
Conclusion | Mesectodermal leiomyoma has distinct clinical features, justifying incisional biopsy before planning further management adapted to its benign nature. |
Last name | SCHALENBOURG |
Initials | A |
Department | Jules Gonin Eye Hospital |
City | Lausanne (VD), CH |
Last name | MORMILE |
Initials | S |
Department | Jules Gonin Eye Hospital |
City | Lausanne (VD), CH |
Last name | UFFER |
Initials | S |
Department | Jules Gonin Eye Hospital |
City | Lausanne (VD), CH |
Last name | ZOGRAFOS |
Initials | L |
Department | Jules Gonin Eye Hospital |
City | Lausanne (VD), CH |