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TitleRecurring hyphaema as the presenting symptom of a juvenile xanthogranuloma.
PurposeTo report a 13-month old infant with the typical juvenile xanthogranuloma (JXG) skin lesions. She presented to her ophthalmologist with recurrent hyphaema. A lesion of the iris was discovered in the inferior part. The natural history, histological features and treatment of the condition are discussed.
MethodsCase report and review of the medical literature.
ResultsThe diagnosis of JXG was made by biopsy of a skin lesion. Despite topical steroid drops and three subconjunctival steroid injections, there was no regression of the iris mass. The iris mass subsided after systemic corticosteroid therapy.
ConclusionJuvenile xanthogranuloma is a benign histiocytic cutaneous disorder mainly occurring in children but also affecting the eye. The iris is most commonly involved, but also eyelid, epibulbar lesions, corneal involvement and orbital involvement have been described. JXG of the optic nerve, disc, retina and choroid has rarely been reported.
Author 1
Last nameVANDEWALLE
InitialsE
DepartmentUniversity Hospitals Leuven
CityLeuven
Author 2
Last nameVan Der Hauwaert
InitialsN
DepartmentSint Augustinus Hospital
CityAntwerpen
Author 3
Last nameCasteels
InitialsI
DepartmentUniversity Hospitals Leuven
CityLeuven
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