View abstract

This abstract is assigned to session OB Poster session > in poster area

Title	Corneal complications following use of intraoperative Mitomycin C in filtering surgery.
Abstract Nr.	141

Purpose	To present the corneal complications of the Mitomycin C use that arose three weeks after the application of Mitomycin C during filtering surgery in two patients.
Methods	Clinical observation of diffuse epithelopathy with subepithelial stromal oedema of the cornea in an elderly lady, 81 years of age, three weeks after she underwent a trabeculectomy with Mitomycin C. Another patient, a 76 year old man, first developed an epithelium defect on the central cornea in the third postoperative week after a trabeculectomy with Mitomycin C. Later the corneal stroma melted and resulted in a corneal perforation during the second postoperative month.
Results	Two patients developed serious corneal complications several weeks after the scleral application of Mitomycin C during trabeculectomy.
Conclusion	Serious corneal complications may arise following the intraoperative use of Mitomycin C in filtering surgery. The possible factors that influence the development of the corneal side effects will be discussed.

Author 1

Last name	COPPENS
Initials	G
Department	Department of ophthalmology, University Hospitals, Leuven, B-3000, Belgium
City	Leuven

Author 2

Last name	MAUDGAL
Initials	PC
Department	Department of ophthalmology, University Hospitals, Leuven, B-3000, Belgium
City	Leuven