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TitleOcular leishmaniasis and HIV a case report
Abstract Nr.139
PurposeTo report a case of ocular leishmaniasis treated with combined amfotericine B and glucanthime R (meglumine antimoniate).
MethodsA 39- year- old man from Burkina-Fasso known with HIV and cutaneous Leishmaniasis major treated with HAART and amfotericine B presented with a conjunctival red coloured swelling in both eyes since 10 days. Visual acuity was 20/20 in both eyes. There was no corneal involvement and the rest of the ocular examination was within the normal limits. A biopsy revealed a dense inflammatory infiltration of lymphocytes, plasma cells and neutrophils. Many of these inflammatory cells contained typical amastigotes of Leishmania in their cytosols. No malignancy was noticed.
ResultsSystemic treatment with combined amfotericine B and glucanthimeR led to improvement of the cutaneous lesions and healing of the conjunctival lesions. Also treated with HAART-therapy Viread 245 mg 1x/dag ,Emtriva 200 mg 1x/dag, Stocrin 600 mg 1x/dag.
ConclusionOcular leishmaniasis is a rare and potentially blinding disorder. Combined amfotericine B and glucanthime turned out to be an effective therapy in this particular case.
Author 1
Last nameVAN GRASDORFF
InitialsS
DepartmentUniversity Hospital
CityAntwerp
Author 2
Last nameDe Keizer
InitialsR
DepartmentUniversity Hospital
CityAntwerp
Author 3
Last nameDe Groot
InitialsV
DepartmentUniversity Hospital
CityAntwerp
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