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TitleSubjective versus objective vertical cup-disc-ratio assessment in open angle glaucoma patients
Abstract Nr.1059
PurposeTo evaluate the difference between fundoscopic and confocal scanning vertical cup disc ratio (VCDR) assessment and their respective predictive value for estimating functional glaucomatous damage.
MethodsData from a single eye of open angle glaucoma patients from the Leuven eye study was included: age, gender, intraocular pressure, visual acuity, spherical equivalent, visual field mean deviation and pattern standard deviation, fundoscopic and HRT II VCDR as well as mean retinal nerve fiber layer thickness (mRNFL). Non-parametric tests to compare within and between diagnostic groups were used and receiver-operater curves as well as Bland Altman plots constructed.
ResultsThree hundred and one eyes of 301 subjects with primary open angle and normal tension glaucoma were included. The average VCDR assessed with HRT II was significantly smaller than the fundoscopic measurement (p<0.001). The predictive value of both measurement techniques did not differ in NTG patients but the fundoscopic estimate yielded a significant better predictive potential in severe POAG patients.
ConclusionFundoscopic and confocal scanner estimates of VCDR differ significantly and should not be used interchangeably. In POAG patients with severe glaucoma, a subjective VCDR predicts functional glaucomatous damage significantly better.
Authors 1
Last nameVANDEWALLE
InitialsE
DepartmentUZ Leuven
CityLeuven
Authors 2
Last nameWillekens
InitialsK
DepartmentUZ Leuven
CityLeuven
Authors 3
Last nameVan Keer
InitialsK
DepartmentUZ Leuven
CityLeuven
Authors 4
Last nameAbegao Pinto
InitialsL
DepartmentCentro Hospitalar Lisboa Norte
CityLisabon
Authors 5
Last nameStalmans
InitialsI
DepartmentUZ Leuven
CityLeuven
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