View abstract

This abstract is assigned to sessions

Presentation type	E-poster
Title	Treatment of Metastatic Uveal Melanoma

Purpose	Description of the various treatments and follow-up of metastatic uveal melanoma patients. Assesment whether the introduction of immune checkpoint inhibitors improved survival.
Methods	retrospective single-center study.
Results	121 metastatic uveal melanoma patients were registered. No significant improvement of the survival could be established after the introduction of immune checkpoint inhibitors. Only liver-directed and local oligometastatic approaches were associated with a lower chance of mortality when compared tot immune checkpoint inhibitors (p=0.0025).
Conclusion	Although we documented responses tot immune checkpoint inhibitors, our analyses do not demonstrate an overall survival improvement of checkpoint inhibitors over alternative treatment strategies. However, local treatment options, whether liver-directed or for oligometastatic disease, may be beneficial and should be considerd.
Conflict of interest	No

Authors 1

Last name	MISSOTTEN
Initials	G
Department	Jessa Oogkliniek Hasselt and University Hospitals Leuven
City	Hasselt/Leuven

Authors 2

Last name	Vanaken
Initials	L
Department	Department of Oncology, University Hospitals Leuven
City	Leuven

Authors 3

Last name	Van Ginderdeuren
Initials	R
Department	Department of ophthalmology, University Hospitals Leuven
City	Leuven

Authors 4

Last name	Thal
Initials	D
Department	Department of Pathology, University Hospitals Leuven
City	Leuven

Authors 5

Last name	Bechter
Initials	O
Department	Department of Oncology, University Hospitals Leuven
City	Leuven

Authors 6

Last name	Clement
Initials	P
Department	Department of Oncology, University Hospitals Leuven
City	Leuven