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Title	Long term visual outcome of patients presenting with serpiginous choroiditis
Abstract Nr.	P05

Purpose	To report the long-term evolution, complications, and visual outcome of patients presenting with serpiginous choroiditis, and to compare the therapeutic approaches
Methods	Retrospective analysis of patients diagnosed with active serpiginous choroiditis in two tertiary eye care centres. They were observed or treated with corticosteroids and/or different immunosuppressive regimens. Complete ophthalmologic examinations and Fluorescein Angiographies have been regularly performed.
Results	23 patients (46 eyes) were included. The mean follow-up period was 15 years. F/M ratio was 2. First symptoms appeared at the mean age of 41.5 years (range 20-75). Most usual visual complain was a loss of vision (49%), followed by myodesopsia (20%) and scotoma (11%). Fundus biomicroscopy revealed the disease in 29% of the eyes. The mean period from the first attack up to the last recurrence was 11.8 years. The mean number of recurrences during evolution of the disease in one eye was 2,2. Neovascularization occurred in 11% of the eyes. Final visual acuity was superior or equal to 20/40 in 23/46 eyes (50%), inferior or equal to 20/200 in 18/46 eyes (39%) and superior or equal to 20/100 and inferior or equal to 20/50 in 5/46 eyes (11%). Immunosuppressive agents used from 1988 provide a better control of the disease in case of foveal threat and lead more often to a useful final visual acuity.
Conclusion	Serpiginous choroiditis is a rare but severe condition requiring long term aggressive immunosuppressive therapy to maintain visual function. The best therapeutic strategy needs to be standardized.

Author 1

Last name	LEFEBVRE
Initials	P
Department	ERASME
City	BRUSSELS

Author 2

Last name	CASPERS
Initials	L
Department	BRUGMANN & SAINT PIERRE
City	BRUSSELS

Author 3

Last name	FARDEAU
Initials	C
Department	PITIE SALPETRIERE
City	PARIS

Author 4

Last name	CASSOUX
Initials	N
Department	PITIE SALPETRIERE
City	PARIS

Author 5

Last name	BODAGHI
Initials	B
Department	PITIE SALPETRIERE
City	PARIS

Author 6

Last name	LEHOANG
Initials	P
Department	PITIE SALPETRIERE
City	PARIS