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Deze abstract is toegekend aan sessie SBO-BOG free papers: Medische retina en Uveïtis/ Rétine médicale et uvéite
TitelTreatment of retinal angiomatous proliferation: comparison between intravitreal bevacizumab and triamcinolone acetonide associated with verteporfin photodynamic therapy
Abstract Nr.143
DoelTo evaluate and compare the efficacy of intravitreal bevacizumab and triamcinolone acetonide in the management of retinal angiomatous proliferation (RAP) in combination with verteporfin photodynamic therapy (PDT).
MethodesRetrospective non-randomised study of 23 eyes of 20 patients diagnosed with RAP.
Patients were treated with verteporfin photodynamic therapy ( 6 mg/m² ) in combination either with bevacizumab ( 1,25 mg/0,05 ml ) either with triamcinolone acetonide ( 4 mg/0,1 ml ).Visual acuity measurement , optical coherence tomography and fluorescein angiography were performed.
ResultatenNine eyes of 8 patients were treated with a mean of 1,6 intravitreal injections of triamcinolone acetonide in combination with PDT. The mean visual acuity improved from 0,29 pre-treatment to 0,44 after a mean follow-up of 15,7 months.
Fourteen eyes of 12 patients were treated with a mean of 5 intravitreal injections of bevacizumab in combination with PDT. The mean visual acuity improved from 0,24 pre-treatment to 0,31 after a mean follow-up of 14,8 months.
The 23 treated eyes showed regression of exudative symptoms.
There were no major complications in both groups.
ConclusieIntravitreal bevacizumab and triamcinolone acetonide in combination with verteporfin photodynamic therapy are both efficient and safe in the management of retinal angiomatous proliferation. In our series , intravitreal injection of triamcinolone acetonide seemed to provide a better final visual outcome with need of less injections.
Auteur 1
NaamGUAGNINI
InitialenA-P
InstituutCliniques Universitaires Saint-Luc
StadBruxelles
Auteur 2
NaamSNYERS
InitialenB
InstituutCliniques Universitaires Saint-Luc
StadBruxelles
Auteur 3
NaamKOZYREFF
InitialenA
InstituutCliniques Universitaires Saint-Luc
StadBruxelles
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