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Deze abstract is toegekend aan sessie SB0-BOG Free paper: Glaucoma/Glaucome

Titel	Micropulse Diode Laser Trabeculoplasty (810 nm)(MDLT) and Argon Laser Trabeculoplasty (ALT) in the treatment of glaucoma : comparative short and medium-term safety profile and IOP efficacy
Abstract Nr.	226

Doel	Prospective, consecutive, randomized comparative study aiming at assessing the safety and the IOP lowering effect after Micropulse Diode Laser Trabeculoplasty (810 nm) (MDLT) and Argon Laser Trabeculoplasty (ALT) in glaucomatous patients.
Methodes	26 patients (mean age: 67.6 years) (31 eyes) were randomly assigned to undergo either MDLT (16 eyes) (66 applications, 100 ms, 0.6mJ/pulse, 300 µm) or ALT ( 15 eyes) over 180°. In 5 patients, MDLT was done in one eye and ALT in the other eye. Patients were followed for early IOP spikes and anterior segment inflammation. IOP was recorded at 2 hours, 1, 2 weeks, 1,2,3 months after trabeculoplasty and every 3 months thereafter.
Resultaten	Both groups were well-matched for age, glaucoma type, previous laser or surgical procedure, pre-treatment meds. Mean follow-up was 2.6+/-1.3 months for MDLT and 3.4+/-2.0 in ALT (p>0.05). Mean pre-treatment IOP was 20.8+/-3.8 mmHg and 21.5+/-4.2 in MDLT and ALT respectively (p>0.05). At the last visit, IOP was 17.5+/-4.7mm Hg in MDLT and 15.4+/-2.5 mm Hg in ALT (p>0.05). The percentage of mean IOP reduction was higher in ALT (28.3%) than in MDLT (16.8%) (p=0.011). Number of medications was significantly lower in MDLT (2.3+/-0.6) than in ALT (2.9+/-0.7) at the last visit (p=0.03). Anterior segment inflammation was absent or mild in both procedures. MDLT was associated with early moderate IOP spike in one eye.
Conclusie	MDLT seemed to be better tolerated than ALT, to exhibit an excellent safety profile and to induce short and medium-term IOP reduction slightly lower than ALT. Its selective thermal interaction with only trabecular pigmented cells have to be considered in the therapeutical decision

Auteur 1

Naam	MUSCHART
Initialen	F
Instituut	St Luc University Hospital
Stad	Brussels

Auteur 2

Naam	Pourjavan
Initialen	S
Instituut	St Luc University Hopistal
Stad	Brussels

Auteur 3

Naam	Detry-Morel
Initialen	M
Instituut	St Luc University Hopistal
Stad	Brussels