THE BELGIAN OPHTHALMIC ASSOCIATIONS
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| Titel | Short-term influence of antiglaucomatous medications on the Ocular Pulse Amplitude (OPA) measured with the Dynamic Contour Tonometer Pascal |
| Abstract Nr. | P13 |
| Doel | To assess the short and medium-term influence of antiglaucomatous treatment on the OCular Pulse Amplitude (OPA) value by the Dynamic Contour Tonometer Pascal (DCT). |
| Methodes | Prospective non-randomized study including 35 eyes of 25 patients (mean age: 63+/-10,9 years) with newly diagnosed POAG or OHT and treated with latanoprost, bimatoprost or Cosopt®. The IOP and OPA were measured with GAT and DCT before starting the study and after 1, 3 and 6 months of treatment. Central corneal thickness (CCT), systolic, diastolic blood pressure (BP) and cardiac frequency were recorded. Pearson coefficient was used to assess correlations. |
| Resultaten | The mean GAT IOP was 25.0+/-5.6 mmHg at baseline,17.7+/-3.6 mmHg, 17.9+/-3.2 mmHg and 17.6+/-3.3 mmHg at 1,3 and 6 months post-treatment respectively (p<0.001). From a mean baseline IOP of 24.2+/-3.9 mm Hg,the mean DCT IOP was 17.9+/-2.6 mmHg,17.6+/-2.5 mmHg, 17.5+/-2.3 mmHg at 1,3 and 6 months (p<0.001). Both mean IOP GAT and DCT were correlated with CCT (p<0.05). GAT and DCT IOP were strongly correlated at all visits. The mean pretreatment OPA was 3.3+/-0.9 mmHg.It was highly significantly reduced to 2.6+/-0.7 mmHg at 1 month, 2.6+/-0.7 mmHg at 3 months and 2.8 +/-0.6 mmHg at 6 months, without difference between the post-treatment visits (regression, p>0.05). The baseline OPA was significantly correlated with DCT IOP, systolic and diastolic BP. It was only correlated with BP at month 1 (p<0.05). The decreases in OPA and IOP were significantly correlated. |
| Conclusie | Antiglaucomatous medications are associated with a significant short-term decrease in OPA which remains stable in the medium-term. |
Auteur 1
| Naam | DETRY |
| Initialen | M |
| Instituut | St Luc University Hospital |
| Stad | Brussels |
Auteur 2
| Naam | JAMART |
| Initialen | J |
| Instituut | St Luc University Hospital |
| Stad | Yvoir |
Auteur 3
| Naam | POURJAVAN |
| Initialen | S |
| Instituut | St Luc University Hospital |
| Stad | Brussels |