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Deze abstract is toegekend aan sessie BGS: Belgian Glaucoma Society
TitelTarget IOP and diurnal IOP fluctuations
Abstract Nr.111
DoelOver the past decade, results from several multicentre clinical trials have confirmed the value of reducing intraocular pressure (IOP) in patients with ocular hypertension or primary open-angle glaucoma. Importantly they have outlined the need to consider a target IOP in an individual glaucomatous patient and not an arbitrary value of 21 mm Hg as usually classically considered. The target IOP corresponds to an estimation of the mean IOP obtained with treatment that is expected to prevent further glaucomatous damage. Target IOP is difficult to assess accurately and in advance in every individual patient and eye. Moreover no degree of IOP is proven to be safe for every patient. This presentation will deal with the criteria that can be used to approach as closely as possible and periodically re-assess the range of the target IOP in an individual.
The role of diurnal IOP fluctuations and long-term IOP variation will be discussed in the second part of this speech.
Although IOP has been found to be more variable in glaucomatous that in healthy eyes, the potential role of diurnal IOP fluctuations in the development or progression of glaucomatous damage has to be further clarified. It has been strongly suggested in a recent past than an abnormal range of daily physiological IOP fluctuation (i.e higher than 5 mm Hg) could be a significant risk factor for glaucomatous damage. However there is still currently insufficient evidence to support both 24-hour IOP fluctuation and IOP variation over periods longer than 24 hours as a risk factor for glaucoma development or progression.
Auteur 1
NaamDETRY
InitialenM
InstituutSt Luc University Hospital
StadBrussels
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