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Deze abstract is toegekend aan sessie SBO-BOG Free papers: Miscellaneous
TitelOptic neuropathy in Graves’ orbitopathy: are Visual evoked potentials a helpful test?
Abstract Nr.147
DoelThe aim of the study is to determine the accuracy of the pattern visual evoked potential (P-VEP), compared to the clinical tests, for an early detection of optic neuropathy in Graves’orbitopathy.
MethodesWe retrospectively reviewed the clinical and VEP data of 33 patients with GO and complains or suspicious signs of visual dysfunction. The mean age was 51,7 y (26-77), 19 were female. The P-VEP responses (P100) were recorded at Oz with 4 different size of checkerboard stimulus: 1°arc, 30’, 15’, 7.5’. The flash VEP (F-VEP) responses were also recorded in 27 patients. VEP structural and latency abnormalities (> 3 SD) were taken into account. The recorded clinical data included best corrected visual acuity, Ishihara test, exophthalmometry, motility, relative afferent pupillary defect, clinical activity score, anterior biomicroscopy , tonometry, visual field, fundus examination. Correlations between the VEP latencies and the clinical data were also investigated.
ResultatenP100 structural abnormalities were observed in 18 eyes (12 pts). P-100 latencies were significantly (> 3SD) abnormal in 24 eyes (15 pts). The 15’ and/or 7, 5’ stimulus size induced abnormal responses in 42 eyes, whereas responses to 1° and 30’ size stimulus were abnormal in 21 eyes F-VEP responses were abnormal in 27 eyes (19 patients). We observed the most significant correlation between the VEP latencies and the exophthalmos, motility dysfunction,

ConclusieUsing different size, and particularly small size, of checkerboard stimulus for P-VEP seems to increase the sensitivity for a very early diagnosis of subclinical optic neuropathy in GO.
Auteur 1
NaamBOSCHI
InitialenA
InstituutOphthalmology, Université Catholique de Louvain
StadBrussels
Auteur 2
Naamde Tourtchaninoff
InitialenM
InstituutNeurology , UCL
StadBrussels
Auteur 3
NaamDaumerie
InitialenCh
InstituutEndocrinology,UCL
StadBrussels
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