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TitelMesectodermal leiomyoma: current diagnostic approach and management
DoelMesectodermal leiomyoma is a rare benign intraocular tumor, on which mostly only single case reports (nr:~60), based on coincidental histopathological findings, have been published. Clear diagnostic or therapeutic guidelines have not been published yet.
MethodesWe studied retrospectively 5 consecutive leiomyoma cases, observed or treated since 2001. We present their clinical features, differential diagnostic approach, and management.
ResultatenReferral diagnosis of all cases was uveal melanoma. All tumors were well delineated and originated in the ciliary body (4) or anterior choroid (1). Median thickness was 7.6 mm (4.0-12.6), with low internal reflectivity and a supraciliary/-choroidal location on US examination (UBM/20/10 MHz). Suspicion of leiomyoma (4) or melanocytoma (1) had motivated incisional biopsy as a diagnostic approach. Management consisted of specific surgical incision (3) or periodic observation (2).
ConclusieMesectodermal leiomyoma has distinct clinical features, justifying incisional biopsy before planning further management adapted to its benign nature.
Auteur 1
NaamSCHALENBOURG
InitialenA
InstituutJules Gonin Eye Hospital
StadLausanne (VD), CH
Auteur 2
NaamMORMILE
InitialenS
InstituutJules Gonin Eye Hospital
StadLausanne (VD), CH
Auteur 3
NaamUFFER
InitialenS
InstituutJules Gonin Eye Hospital
StadLausanne (VD), CH
Auteur 4
NaamZOGRAFOS
InitialenL
InstituutJules Gonin Eye Hospital
StadLausanne (VD), CH
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