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Cet abstract a été assigné à session OB Free papers: Glaucoma

Titre	Assessing the functionality and biocompatibility of a wireless contact lens sensor for 24 hour-intraocular pressure monitoring in volunteers: preliminary results.
Abstract Nr.	327

But	In vitro studies in porcine eyes have demonstrated a good correlation between induced intraocular pressure variations and corneal curvature changes, using a contact lens with an embedded microfabricated strain gauge. Continuous 24 hour-intraocular pressure (IOP) monitoring to detect large diurnal fluctuation is currently an unmet clinical need. The precision of signal transmission and biocompatibility of 24 hour contact lens sensor wear (SENSIMED Triggerfish®) was evaluated in humans.
Méthodes	After full eye examination in 10 healthy volunteers, a 8.7 mm radius contact lens sensor and an orbital bandage containing a loop antenna were applied and connected to a portable recorder. Best corrected visual acuity and position, lubrication status and mobility of the sensor were assessed after 5 and 30 minutes, 4, 7 and 24 hours. Subjective comfort was scored and activities documented in a logbook. After sensor removal full eye examination was repeated, and the registration signal studied.
Résultats	The comfort score was high and did not fluctuate significantly, except at the 7 hour-visit. The mobility of the contact lens was minimal but its lubrication remained good. Best corrected visual acuity was significantly reduced during the sensor wear and immediately after its removal. Three patients developed mild corneal staining. In all but one participant we obtained a registration curve with visible ocular pulse amplitude.
Conclusion	This 24 hour-trial confirmed the functionality and biocompatibility of SENSIMED Triggerfish® wireless contact lens sensor for IOP-monitoring in volunteers. Further studies with a range of different contact lens sensor radii are indicated.

Auteur 1

Nom	DE SMEDT
Initiales	S
Institut	Centre du Glaucome, Clinique Montchoisi
Ville	Lausanne

Auteur 2

Nom	Mermoud
Initiales	A
Institut	Centre du Glaucome, Clinique Montchoisi
Ville	Lausanne