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Cet abstract a été assigné à session SB0-BOG Free paper: Glaucoma/Glaucome

Titre	Micropulse Diode Laser Trabeculoplasty (810 nm)(MDLT) and Argon Laser Trabeculoplasty (ALT) in the treatment of glaucoma : comparative short and medium-term safety profile and IOP efficacy
Abstract Nr.	226

But	Prospective, consecutive, randomized comparative study aiming at assessing the safety and the IOP lowering effect after Micropulse Diode Laser Trabeculoplasty (810 nm) (MDLT) and Argon Laser Trabeculoplasty (ALT) in glaucomatous patients.
Méthodes	26 patients (mean age: 67.6 years) (31 eyes) were randomly assigned to undergo either MDLT (16 eyes) (66 applications, 100 ms, 0.6mJ/pulse, 300 µm) or ALT ( 15 eyes) over 180°. In 5 patients, MDLT was done in one eye and ALT in the other eye. Patients were followed for early IOP spikes and anterior segment inflammation. IOP was recorded at 2 hours, 1, 2 weeks, 1,2,3 months after trabeculoplasty and every 3 months thereafter.
Résultats	Both groups were well-matched for age, glaucoma type, previous laser or surgical procedure, pre-treatment meds. Mean follow-up was 2.6+/-1.3 months for MDLT and 3.4+/-2.0 in ALT (p>0.05). Mean pre-treatment IOP was 20.8+/-3.8 mmHg and 21.5+/-4.2 in MDLT and ALT respectively (p>0.05). At the last visit, IOP was 17.5+/-4.7mm Hg in MDLT and 15.4+/-2.5 mm Hg in ALT (p>0.05). The percentage of mean IOP reduction was higher in ALT (28.3%) than in MDLT (16.8%) (p=0.011). Number of medications was significantly lower in MDLT (2.3+/-0.6) than in ALT (2.9+/-0.7) at the last visit (p=0.03). Anterior segment inflammation was absent or mild in both procedures. MDLT was associated with early moderate IOP spike in one eye.
Conclusion	MDLT seemed to be better tolerated than ALT, to exhibit an excellent safety profile and to induce short and medium-term IOP reduction slightly lower than ALT. Its selective thermal interaction with only trabecular pigmented cells have to be considered in the therapeutical decision

Auteur 1

Nom	MUSCHART
Initiales	F
Institut	St Luc University Hospital
Ville	Brussels

Auteur 2

Nom	Pourjavan
Initiales	S
Institut	St Luc University Hopistal
Ville	Brussels

Auteur 3

Nom	Detry-Morel
Initiales	M
Institut	St Luc University Hopistal
Ville	Brussels