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Cet abstract a été assigné à session SBO-BOG Free papers: Miscellaneous
TitreTreatment of conjunctival melanoma
Abstract Nr.149
ButTo describe the diagnosis, treatment and outcome of 200 conjunctival melanomas treated between 1950 and 2005 retrospectively.
MéthodesRetrospective descriptive study.
RésultatsThe origin of the conjunctival melanoma was nevus (12), primary acquired melanosis (PAM) (113), de novo (52), or not known (23). Out of 200 patients, 114 had a local recurrence, during the median follow-up of 7.1 years (range 1.5-50.5 years). Non-epibulbar localisation was the most important risk factor for local recurrence and survival. Significantly fewer local recurrences occurred with tumors initially treated with excision and adjuvant brachytherapy ( Sr 90 ), in comparison with tumors treated with excision only or with excision with cryotherapy. Mean tumor thickness was 2.1 mm (standard deviation 1.9 mm). Tumor thickness was also a prognostic factor for survival.
Forty three patients had regional lymph node metastases, mostly to the preauricular lymph nodes. Fifty patients had a distant metastases mainly to the liver and lung.
Tumor-related survival was 86.5% at 5 years, 72% at 10 years and 67% at 15 years.
ConclusionPoor survival was associated with a non-epibulbar melanoma and thicker tumors. In this study, fewer local recurrences were seen when excision was combined by brachytherapy.
Auteur 1
NomMISSOTTEN
InitialesGS
InstitutLeiden University Medical Center
VilleLeiden
Auteur 2
Nomde Wolff-Rouendaal
InitialesD
InstitutLeiden University Medical Center
VilleLeiden
Auteur 3
NomTassignon
InitialesMJ
InstitutUniversitair Ziekenhuis Antwerpen
VilleAntwerpen
Auteur 4
Nomde Keizer
InitialesRJ
InstitutUniversitair Ziekenhuis Antwerpen en Leiden University Medical Center
VilleAntwerpen
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