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TitrePhysiological short-time variability of ocular pulse amplitude (OPA) measured by dynamic contour tonometers (DCT) in healthy subjects
ButThe Pascal® dynamic tonometer is a non-applanation contact tonometer. It measures the systolic and diastolic IOP and their difference to determine OPA. By recording the pulsatile component of ocular blood flow the OPA could provide an indirect measurement of the choroidal perfusion. It has been suggested that OPA could be an indirect risk factor for glaucoma progression. Still the characteristics of OPA remain unclear. In a prior study we determined the diurnal variability of OPA. Here we aimed to assess the short-time variability of OPA in healthy persons.

MéthodesThe left eyes of 30 healthy subjects were included in this prospective study. The IOP was measured twice by Goldmann applanation tonometers (GAT) followed by 3 consecutive measurements by DCT 10 min later. Pachymetry, arterial blood pressure and pulse rate were measured after IOP measurements. These measurements were repeated with an interval of fifteen days at the same hour of the first measurements. Student Test was used to assess the difference and the Pearson correlation was used to assess the correlation between the various parameters.

RésultatsThe mean age was 41 ± 12 years. The mean IOP at the first visit was 13.6 ± 2.9 mmHg by GAT and 14.3 ± 2.2 mmHg by DCT. The mean OPA was 2.4 ± 0.9 mmHg (0.8 to 4.3 mmHg) at the first visit.
The mean IOP at the second visit was 13.4 ± 3.2 by GAT and 15.0 ± 2.5 mmHg by DCT. The mean OPA was 2.6 ± 1.0 (0.9 to 5.8) mmHg at the second visit.
ConclusionThere was no significant difference in both OPA measurements. This parameter remains stable in a short-time interval in healthy subjects.

Auteur 1
NomMUSTAKA
InitialesL
InstitutCliniques universitaires St. Luc, UCL
VilleBruxelles
Auteur 2
NomDETRY-MOREL
InitialesM
InstitutCliniques universitaires St. Luc, UCL
VilleBruxelles
Auteur 3
NomPOURJAVAN
InitialesS
InstitutCliniques universitaires St. Luc, UCL
VilleBruxelles
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