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TitreEfficacy of selective trabeculoplasty in the treatment of primary open-angle glaucoma
ButSince selective laser trabeculoplasty (SLT) produces significantly less disturbance to the trabecular meshwork and more safety, it has potential to replace argon laser trabeculoplasty (ALT) as the standard procedure to treat open angle glaucoma. Since SLT has been found to have a better success rate when performed the 360 degrees of the trabecular meshwork compared to 180 degrees, we investigate the outcomes of 360° selective laser trabeculoplasty (SLT) in the treatment of primary open-angle glaucoma.
MéthodesIn a non-randomized, prospective clinical study, 80 patients (104 eyes) with progressive POAG or/and medically uncontrolled intraocular pressure underwent SLT. A total of 100+/- 5 adjacent but non overlapping spots were placed over the 360 degrees of the trabecular meshwork using a 532 nm, Q-switched ,Nd:Yag laser at energy levels ranging from 0.5-1.0 mJ per pulse. After SLT, the hypotensive medication during the study period remained unchanged. All patients were observed before and 1 hour, 3 and 6 months after the treatment. Thirty eight of them completed the 12 months follow-up period. Successful SLT defined as having a SLT induced intraocular pressure (IOP) reduction of >or=20% at any post-treatment follow up.
RésultatsThe average pre-operative IOP was (19.5 +/- 7) mm Hg. The mean IOP reduction from baseline were 3.5 mm Hg (20.7%), 3.9 mm Hg (21.3%) 3 months after the SLT, 3.2 mm Hg (18.6%) 6 months after the SLT, 2.2 mm Hg (14.6%) 12 months after the SLT. Adverse reactions were minimal, including conjunctival injection, mild anterior chamber reaction, and transient pressure spike. In one eye, reversible corneal edema was observed.
ConclusionSLT is an effective method to lower IOP in POAG patients. Regards to its safety profile, SLT may be a repeatable therapy option for patients who escape to its effect with time.
Auteur 1
NomCOLLIGNON
InitialesN
VilleLiège
Auteur 2
NomCREVECOEUR
InitialesL
VilleLiège
Auteur 3
NomGUILLAUME
InitialesS
VilleLiège
Auteur 4
NomTRABELSKI
InitialesO
VilleLiège
Auteur 5
NomTHYS
InitialesJ
VilleLiège
Auteur 6
NomHUA
InitialesM
VilleLiège
Auteur 7
NomCOLLIGNON
InitialesJ
VilleLiège
Auteur 8
NomRAKIC
InitialesJM
VilleLiège
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