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Deze abstract is toegekend aan sessie OB Free papers: Oncologie
TitelEpistaxis or Epiphora as sign for extension of a conjunctival melanoma. A series of six patients with nasolacrimal recurrence
Abstract Nr.332
DoelTo characterize malignant conjunctival melanomas with extension and recurrence in the lacrimal duct and nose.
MethodesLocalization of the primary tumor and recurrences of 210 conjunctival melanomas treated in the Netherlands were reviewed for orbital and nasal tumors (1978-2008). On the basis of these cases and literature data, characteristics for lacrimal duct and nose extension and metastasis were reviewed.
ResultatenSix patients (3%) showed a secondary conjunctival melanoma in the nose. Two of the six primary tumors were epibulbar, the other 4 were multifocal tumors involving the fornix. All primary conjunctival melanomas were associated with primary acquired melanosis (PAM). During follow-up period (mean 139 ± 37 months; median 105 months) two patients developed metastases, and died during follow-up.
ConclusieOphthalmologists treating conjunctival melanoma should be aware of the possible extension of conjunctival melanomas in the lacrimal duct and nose, especially in non-epibulbar cases associated with PAM. Screening for conjunctival melanoma recurrences should include the active questioning of epiphora, nose obstructions and epistaxis.
Auteur 1
NaamMISSOTTEN
InitialenGS
InstituutLeiden University Medical Center, Nederland & Catholic University Leuven, België
StadLeuven - Leiden
Auteur 2
NaamGambrelle
InitialenJ
InstituutLyon University Hospital, France
StadLyon
Auteur 3
NaamDe Wolff-Rouendaal
InitialenD
InstituutLeiden University Medical Center, Nederland
StadLeiden
Auteur 4
NaamDe Keizer
InitialenRJ
InstituutLeiden University Medical Center, Nederland & Antwerp University, België
StadLeiden - Antwerpen
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