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Cet abstract a été assigné à session OB Free papers: Oncologie
TitreEpistaxis or Epiphora as sign for extension of a conjunctival melanoma. A series of six patients with nasolacrimal recurrence
Abstract Nr.332
ButTo characterize malignant conjunctival melanomas with extension and recurrence in the lacrimal duct and nose.
MéthodesLocalization of the primary tumor and recurrences of 210 conjunctival melanomas treated in the Netherlands were reviewed for orbital and nasal tumors (1978-2008). On the basis of these cases and literature data, characteristics for lacrimal duct and nose extension and metastasis were reviewed.
RésultatsSix patients (3%) showed a secondary conjunctival melanoma in the nose. Two of the six primary tumors were epibulbar, the other 4 were multifocal tumors involving the fornix. All primary conjunctival melanomas were associated with primary acquired melanosis (PAM). During follow-up period (mean 139 ± 37 months; median 105 months) two patients developed metastases, and died during follow-up.
ConclusionOphthalmologists treating conjunctival melanoma should be aware of the possible extension of conjunctival melanomas in the lacrimal duct and nose, especially in non-epibulbar cases associated with PAM. Screening for conjunctival melanoma recurrences should include the active questioning of epiphora, nose obstructions and epistaxis.
Auteur 1
NomMISSOTTEN
InitialesGS
InstitutLeiden University Medical Center, Nederland & Catholic University Leuven, België
VilleLeuven - Leiden
Auteur 2
NomGambrelle
InitialesJ
InstitutLyon University Hospital, France
VilleLyon
Auteur 3
NomDe Wolff-Rouendaal
InitialesD
InstitutLeiden University Medical Center, Nederland
VilleLeiden
Auteur 4
NomDe Keizer
InitialesRJ
InstitutLeiden University Medical Center, Nederland & Antwerp University, België
VilleLeiden - Antwerpen
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