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TitreOptic nerve head hemorrhage and vitreous traction
Abstract Nr.1036
ButDuring posterior vitreous detachment (PVD) formation, the posterior hyaloid remains attached to the optic disc for a certain period. It can exert traction with development of optic nerve head hemorrhages (ONHH). ONHH are known to be associated with glaucomatous progression and retinal nerve fiber layer (RNFL) defects. Therefore, this study aims at investigating the relationship between PVD formation and ONHH in open angle glaucoma patients.
MéthodesPatients presenting with an ONHH were included from November 2014 on. They underwent a comprehensive ophthalmological investigation, automated visual field test (Humphrey or Octopus), confocal scanner (HRT III), OCT scan (HRT-Spectralis) and stereographic photos of the optic nerve head. This study is part of a larger study (clinicaltrial.gov NCT02290795) investigating vitreopapillary traction (VPT).
RésultatsThirty eyes of 30 patients were included (20 normal tension and 10 primary open angle glaucoma). Fourteen out of 30 eyes (46,7%) had concomitant VPT and 9 had a complete PVD. Thirteen ONHHs were located inferotemporal, 7 superotemporal, 7 temporal and 3 nasal. In the non-VPT group 6 out of 16 (37,5%) eyes showed matching retinal nerve fiber layer defects, with 8 out of 14 (57,1%) in the VPT subgroup (p>0,05).
ConclusionVPT is a frequent finding in glaucomatous patients with ONHH, and could be a confounding factor in glaucoma assessment. Future work is needed to determine the frequency of VPT in glaucoma patients without ONHH and in non-glaucomatous individuals, and to gain insight in the role of VPT in the pathogenesis of glaucomatous optic neuropathy.
Auteur 1
NomWILLEKENS
InitialesK
InstitutUZ Leuven
VilleLeuven
Auteur 2
NomAbegão Pinto
InitialesL
InstitutLisbon university
VilleLissabon
Auteur 3
NomVandewalle
InitialesE
InstitutUZ Leuven
VilleLeuven
Auteur 4
NomStalmans
InitialesP
InstitutUZ Leuven
VilleLeuven
Auteur 5
NomStalmans
InitialesI
InstitutUZLeuven
VilleLeuven
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