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TitreEffect of dexamethasone intravitreal implant in the treatment of noninfectious uveitis
Abstract Nr.2039
ButTo investigate the effect of dexamethasone intravitreal implant (Ozurdex; Allergan, Inc) in noninfectious uveitis.
MéthodesCharts of patients with noninfectious uveitis treated by dexamethasone intravitreal implants were reviewed in a retrospective study. Uveitis etiologies, treatment indications, visual acuity, central retinal thickness measured by optical coherence tomography, intraocular pressure, number of injections were collected. Parameters were analyzed before injection, after 5-6 weeks (short follow-up) and 4-5 months (long follow-up) post-Ozurdex injection.
RésultatsWe included 14 patients (20 eyes, 26 implants injections). Before injections, mean visual acuity was 0.4±0.5 logMAR and improved to 0.3±0.5 logMAR at short time follow-up and to 0.3±0.5 logMAR at long time follow-up. Macular thickness has decreased by 81.4±99.4 µm at short time follow-up and 61.3±139.5 µm at long time follow-up. Mean intraocular pressure was 16±5 mmHg before injections, 18±6 mmHg at short time follow-up and 14±3 mmHg at long time follow-up.
ConclusionIn noninfectious uveitis, dexamethasone implant can improve visual acuity and decrease macular thickness without significant increase of intraocular pressure. Although the effect seems limited in time.
Auteur 1
NomFRERE
InitialesA
InstitutCHU Saint-Pierre and CHU Brugmann
VilleBrussels
Auteur 2
NomJanssens
InitialesX
InstitutCHU Saint-Pierre
VilleBrussels
Auteur 3
NomMakhoul
InitialesD
InstitutCHU Saint-Pierre and CHU Brugmann
VilleBrussels
Auteur 4
NomJudice
Initialesl
InstitutCHU Saint-Pierre and CHU Brugmann
VilleBrussels
Auteur 5
NomPostelmans
InitialesL
InstitutCHU Brugmann
VilleBrussels
Auteur 6
NomLefebvre
InitialesP
InstitutCHU Saint-Pierre
VilleBrussels
Auteur 7
NomCaspers
InitialesL
InstitutCHU Saint-Pierre
VilleBrussels
Auteur 8
NomMélot
InitialesC
InstitutErasme Academic Hospital
VilleBrussels
Auteur 9
NomWillermain
InitialesF
InstitutCHU Saint-Pierre
VilleBrussels
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