THE BELGIAN OPHTHALMIC ASSOCIATIONS
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This abstract is assigned to session SB0-BOG Free paper: Glaucoma/Glaucome
| Title | Micropulse Diode Laser Trabeculoplasty (810 nm)(MDLT) and Argon Laser Trabeculoplasty (ALT) in the treatment of glaucoma : comparative short and medium-term safety profile and IOP efficacy |
| Abstract Nr. | 226 |
| Purpose | Prospective, consecutive, randomized comparative study aiming at assessing the safety and the IOP lowering effect after Micropulse Diode Laser Trabeculoplasty (810 nm) (MDLT) and Argon Laser Trabeculoplasty (ALT) in glaucomatous patients. |
| Methods | 26 patients (mean age: 67.6 years) (31 eyes) were randomly assigned to undergo either MDLT (16 eyes) (66 applications, 100 ms, 0.6mJ/pulse, 300 µm) or ALT ( 15 eyes) over 180°. In 5 patients, MDLT was done in one eye and ALT in the other eye. Patients were followed for early IOP spikes and anterior segment inflammation. IOP was recorded at 2 hours, 1, 2 weeks, 1,2,3 months after trabeculoplasty and every 3 months thereafter. |
| Results | Both groups were well-matched for age, glaucoma type, previous laser or surgical procedure, pre-treatment meds. Mean follow-up was 2.6+/-1.3 months for MDLT and 3.4+/-2.0 in ALT (p>0.05). Mean pre-treatment IOP was 20.8+/-3.8 mmHg and 21.5+/-4.2 in MDLT and ALT respectively (p>0.05). At the last visit, IOP was 17.5+/-4.7mm Hg in MDLT and 15.4+/-2.5 mm Hg in ALT (p>0.05). The percentage of mean IOP reduction was higher in ALT (28.3%) than in MDLT (16.8%) (p=0.011). Number of medications was significantly lower in MDLT (2.3+/-0.6) than in ALT (2.9+/-0.7) at the last visit (p=0.03). Anterior segment inflammation was absent or mild in both procedures. MDLT was associated with early moderate IOP spike in one eye. |
| Conclusion | MDLT seemed to be better tolerated than ALT, to exhibit an excellent safety profile and to induce short and medium-term IOP reduction slightly lower than ALT. Its selective thermal interaction with only trabecular pigmented cells have to be considered in the therapeutical decision |
Author 1
| Last name | MUSCHART |
| Initials | F |
| Department | St Luc University Hospital |
| City | Brussels |
Author 2
| Last name | Pourjavan |
| Initials | S |
| Department | St Luc University Hopistal |
| City | Brussels |
Author 3
| Last name | Detry-Morel |
| Initials | M |
| Department | St Luc University Hopistal |
| City | Brussels |