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This abstract is assigned to session SBO-BOG Free papers: Chirurgie retina en vitreum/chirurgie rétine et vitré

Title	Preoperative eye disinfection in vitrectomy surgery
Abstract Nr.	126

Purpose	The incidence of postoperative infection after any intra-ocular surgery or intravitreal injection is approximately 1/1500. Pre-operative application of antibiotic drops is sometimes advocated, but this may induce bacterial resistance. Recently, an antiseptic solution of hexamedinedi-isetionaat (1mg/ml) became available (Desomedine®) for preoperative eye disinfection. Using an antiseptic agent rather than an antibiotic drop may reduce the risk of endoftalmitis without inducing bacterial resistance. The aim of this study is to evaluate the sterilizing effect of Desomedine on the conjunctiva, comparing its effect to a popular antibiotic drug: ofloxacine (Trafloxal®).
Methods	Methods: patients scheduled for a primary vitrectomy were asked to apply a drop of either Trafloxal or Desomedine 4 times daily five days before the surgery. After draping of the patient, but before the routine conjunctival wash with an iodine antiseptic, a conjunctival smear was taken with a Qtip and applied on standard bacterial culturing dishes. Bacterial growth was evaluated by a masked observer.
Results	In total, 60 patients are included in this study: 20 using Desomedine, 20 using Trafloxal, and 20 patients not using any preoperative drops as control samples. Statistical comparison between the three study arms will be performed to evaluate whether preoperative disinfection is useful and which product (antiseptic or antibiotic) is preferred.

Author 1

Last name	VANINBROUKX
Initials	I
Department	UZ Leuven
City	Leuven

Author 2

Last name	Van Calster
Initials	J
Department	UZ Leuven
City	Leuven

Author 3

Last name	Spileers
Initials	W
Department	UZ Leuven
City	Leuven

Author 4

Last name	Verhaegen
Initials	J
Department	UZ Leuven
City	Leuven

Author 5

Last name	Stalmans
Initials	P
Department	UZ Leuven
City	Leuven