Title | Effect of dexamethasone intravitreal implant in the treatment of noninfectious uveitis |
Abstract Nr. | 2039 |
Purpose | To investigate the effect of dexamethasone intravitreal implant (Ozurdex; Allergan, Inc) in noninfectious uveitis. |
Methods | Charts of patients with noninfectious uveitis treated by dexamethasone intravitreal implants were reviewed in a retrospective study. Uveitis etiologies, treatment indications, visual acuity, central retinal thickness measured by optical coherence tomography, intraocular pressure, number of injections were collected. Parameters were analyzed before injection, after 5-6 weeks (short follow-up) and 4-5 months (long follow-up) post-Ozurdex injection. |
Results | We included 14 patients (20 eyes, 26 implants injections). Before injections, mean visual acuity was 0.4±0.5 logMAR and improved to 0.3±0.5 logMAR at short time follow-up and to 0.3±0.5 logMAR at long time follow-up. Macular thickness has decreased by 81.4±99.4 µm at short time follow-up and 61.3±139.5 µm at long time follow-up. Mean intraocular pressure was 16±5 mmHg before injections, 18±6 mmHg at short time follow-up and 14±3 mmHg at long time follow-up. |
Conclusion | In noninfectious uveitis, dexamethasone implant can improve visual acuity and decrease macular thickness without significant increase of intraocular pressure. Although the effect seems limited in time. |
Last name | FRERE |
Initials | A |
Department | CHU Saint-Pierre and CHU Brugmann |
City | Brussels |
Last name | Janssens |
Initials | X |
Department | CHU Saint-Pierre |
City | Brussels |
Last name | Makhoul |
Initials | D |
Department | CHU Saint-Pierre and CHU Brugmann |
City | Brussels |
Last name | Judice |
Initials | l |
Department | CHU Saint-Pierre and CHU Brugmann |
City | Brussels |
Last name | Postelmans |
Initials | L |
Department | CHU Brugmann |
City | Brussels |
Last name | Lefebvre |
Initials | P |
Department | CHU Saint-Pierre |
City | Brussels |
Last name | Caspers |
Initials | L |
Department | CHU Saint-Pierre |
City | Brussels |
Last name | Mélot |
Initials | C |
Department | Erasme Academic Hospital |
City | Brussels |
Last name | Willermain |
Initials | F |
Department | CHU Saint-Pierre |
City | Brussels |