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This abstract is assigned to session AOB Poster session2
TitleEffect of dexamethasone intravitreal implant in the treatment of noninfectious uveitis
Abstract Nr.2039
PurposeTo investigate the effect of dexamethasone intravitreal implant (Ozurdex; Allergan, Inc) in noninfectious uveitis.
MethodsCharts of patients with noninfectious uveitis treated by dexamethasone intravitreal implants were reviewed in a retrospective study. Uveitis etiologies, treatment indications, visual acuity, central retinal thickness measured by optical coherence tomography, intraocular pressure, number of injections were collected. Parameters were analyzed before injection, after 5-6 weeks (short follow-up) and 4-5 months (long follow-up) post-Ozurdex injection.
ResultsWe included 14 patients (20 eyes, 26 implants injections). Before injections, mean visual acuity was 0.4±0.5 logMAR and improved to 0.3±0.5 logMAR at short time follow-up and to 0.3±0.5 logMAR at long time follow-up. Macular thickness has decreased by 81.4±99.4 µm at short time follow-up and 61.3±139.5 µm at long time follow-up. Mean intraocular pressure was 16±5 mmHg before injections, 18±6 mmHg at short time follow-up and 14±3 mmHg at long time follow-up.
ConclusionIn noninfectious uveitis, dexamethasone implant can improve visual acuity and decrease macular thickness without significant increase of intraocular pressure. Although the effect seems limited in time.

Authors 1
Last nameFRERE
InitialsA
DepartmentCHU Saint-Pierre and CHU Brugmann
CityBrussels
Authors 2
Last nameJanssens
InitialsX
DepartmentCHU Saint-Pierre
CityBrussels
Authors 3
Last nameMakhoul
InitialsD
DepartmentCHU Saint-Pierre and CHU Brugmann
CityBrussels
Authors 4
Last nameJudice
Initialsl
DepartmentCHU Saint-Pierre and CHU Brugmann
CityBrussels
Authors 5
Last namePostelmans
InitialsL
DepartmentCHU Brugmann
CityBrussels
Authors 6
Last nameLefebvre
InitialsP
DepartmentCHU Saint-Pierre
CityBrussels
Authors 7
Last nameCaspers
InitialsL
DepartmentCHU Saint-Pierre
CityBrussels
Authors 8
Last nameMélot
InitialsC
DepartmentErasme Academic Hospital
CityBrussels
Authors 9
Last nameWillermain
InitialsF
DepartmentCHU Saint-Pierre
CityBrussels
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